SCHEMBL8620657

SCHEMBL8620657

CC(C)CCN1C(=O)C(NC(=O)Oc2ccccc2)C(=O)N(c2ccccc2)c2ccc(F)cc21

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 17/20 0.68
CCKAR P32238 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618163 0.90 CCKBR (0.70) CCKBR
SCHEMBL8615569 0.89 CCKBR (0.73) CCKBR
SCHEMBL8622431 0.88 CCKBR (0.77) CCKBRCCKAR
SCHEMBL8616304 0.87 CCKBR (0.72) CCKBR
SCHEMBL8634884 0.84 CCKBR (0.93) CCKBRCCKAR
SCHEMBL8617148 0.84 CCKBR (0.68) CCKBRCCKAR
SCHEMBL8621037 0.83 CCKBR (0.71) CCKBR
SCHEMBL8621411 0.83 CCKBR (0.67) CCKBR
SCHEMBL8617280 0.83 CCKBR (0.67) CCKBRCCKAR
SCHEMBL8618358 0.82 CCKBR (0.66) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623118-B1 CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE GLAXO WELLCOME SPA (IT) 1998-05-13 EP disclosed
US-5486514-A GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS GLAXO SPA (IT) 1996-01-23 US disclosed