Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL18839954 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL104934 | 0.93 | — | — | |
| Succinic Acid SCHEMBL9508104 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL155053 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL11666802 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL18889846 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL105373 | 0.93 | — | — | |
| Succinic Acid SCHEMBL151456 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL21776708 | 0.93 | LMNA (0.60) | — | |
| Succinic Acid SCHEMBL7116400 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543340-B1 | Process for preparing lactones | TOSOH CORP (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5502217-A | MULTISTAGE PROCESS WITH HYDROGENATION OF MALEIC ACID OR SUCCINIC ACID IN THE PRESENCE OF METAL TO FORM BUTYROLACTONE | TOSOH CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0543340-A1 | Process for preparing lactones | Tosoh Corporation (JP) | 1993-05-26 | — | — | EP | disclosed |