SCHEMBL8620899

SCHEMBL8620899

OC[C@H]1O[C@@H](Cc2ccncn2)[C@H](O)[C@@H]1O

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADA P00813 1/20 0.40
MAPT P10636 1/20 0.38
CDA P32320 1/20 0.38
TYR P14679 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8620895 1.00 ADA (0.40) ADAMAPTCDATYR
SCHEMBL10695824 0.75 SLC5A2 (0.45) ADAMAPTCDA
SCHEMBL802540 0.74 POLB (0.39)
SCHEMBL8620005 0.74 DOT1L (0.44) MAPT
Ribose (Furanose) SCHEMBL27589741 0.74 ADA (0.39) ADAMAPTCDATYR
SCHEMBL30365920 0.67
Ribose (Furanose) SCHEMBL3655770 0.67 MAPT (0.41) ADAMAPTCDATYR
Ribose (Furanose) SCHEMBL7051560 0.67 MAPT (0.41) ADAMAPTCDATYR
Ribose (Furanose) SCHEMBL10818882 0.67 MAPT (0.41) ADAMAPTCDATYR
Ribose (Furanose) SCHEMBL7511471 0.67 MAPT (0.41) ADAMAPTCDATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686150-B1 Process for the preparation of C-nucleosides and C-nucleoside analogues, new C-nucleosides and C-nucleoside analogues and their use MAX DELBRUECK CENTRUM (DE) 1998-05-20 EP disclosed