Sugi Predict

Sugi Predict / Compounds / SCHEMBL10695824

SCHEMBL10695824

SCHEMBL10695824

OC[C@H]1O[C@@H](c2ccncn2)[C@H](O)[C@@H]1O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 7/20 0.45
▸ PYGL P06737 4/20 0.43
▸ HIF1A Q16665 1/20 0.41
▸ MAPT P10636 1/20 0.40
▸ CDA P32320 1/20 0.40
▸ ADA P00813 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25262978 0.81 SLC5A2 (0.49) SLC5A2PYGLMAPTCDA
SCHEMBL28478930 0.81 SLC5A2 (0.49) SLC5A2PYGLMAPTCDA
SCHEMBL21379781 0.79 SLC5A2 (0.51) SLC5A2PYGL
SCHEMBL26113315 0.79 SLC5A2 (0.51) SLC5A2PYGL
SCHEMBL10695058 0.78 FBP1 (0.51) —
SCHEMBL27651692 0.77 SLC5A2 (0.49) SLC5A2PYGL
SCHEMBL28147525 0.77 HIF1A (0.45) SLC5A2PYGLHIF1AMAPTCDA
SCHEMBL8620895 0.75 ADA (0.40) MAPTCDAADA
SCHEMBL8620899 0.75 ADA (0.40) MAPTCDAADA
SCHEMBL6788640 0.74 PYGL (0.45) SLC5A2PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257488-A2 Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process WARNER-LAMBERT COMPANY (US) 1988-03-02 — — EP claimed
EP-0257488-A2 Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process WARNER-LAMBERT COMPANY (US) 1988-03-02 — — EP disclosed