Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.44 |
| ▸ | TACR3 | P29371 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618987 | 0.85 | KMT2A (0.51) | ADORA1ADORA3ALDH1A1KDM4EHPGD | |
| SCHEMBL8620920 | 0.83 | TACR3 (0.43) | TACR3 | |
| SCHEMBL8615669 | 0.82 | TACR3 (0.47) | ALDH1A1KDM4EGAATACR3CYP2C9 | |
| SCHEMBL8613213 | 0.81 | KMT2A (0.47) | ADORA1ADORA3ALDH1A1KDM4EHPGD | |
| SCHEMBL8619721 | 0.79 | MEN1 (0.45) | ALDH1A1KDM4EHPGDCYP2C9MEN1 | |
| SCHEMBL8615863 | 0.79 | TACR3 (0.49) | ALDH1A1KDM4EGAATACR3MEN1 | |
| SCHEMBL8613473 | 0.79 | ADORA1 (0.51) | ADORA1ADORA3ALDH1A1KDM4EHPGD | |
| SCHEMBL8617414 | 0.79 | TACR3 (0.48) | ALDH1A1KDM4EGAATACR3MEN1 | |
| SCHEMBL8614378 | 0.78 | MEN1 (0.44) | ALDH1A1KDM4EHPGDCYP2C9MEN1 | |
| SCHEMBL8619421 | 0.78 | ADORA1 (0.51) | ADORA1ADORA3ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |