Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613213 | 0.96 | KMT2A (0.47) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8617543 | 0.87 | MEN1 (0.46) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8619721 | 0.85 | MEN1 (0.45) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8614378 | 0.85 | MEN1 (0.44) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8620933 | 0.85 | ADORA1 (0.47) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8613481 | 0.84 | KDM4E (0.56) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8613889 | 0.84 | ADORA1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8618698 | 0.84 | PDE10A (0.62) | KMT2AMEN1ALDH1A1CYP1A2GFER | |
| SCHEMBL8615990 | 0.83 | CCR6 (0.57) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8616695 | 0.83 | MEN1 (0.46) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |