SCHEMBL8621263

SCHEMBL8621263

CC(=O)N(C(C)=O)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.52
GAA P10253 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 3/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KMT2A Q03164 1/20 0.44
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
ELANE P08246 2/20 0.42
ATM Q13315 3/20 0.42
CDC25B P30305 1/20 0.42
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11458327 0.82 AKR1C3 (0.48) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL501813 0.81 MAPT (0.77) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL29384309 0.81 MAPT (0.77) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL27617215 0.81 AKR1C3 (0.47) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL28608266 0.80 GAA (0.57) GAAMAPTALDH1A1TP53TSHR
SCHEMBL28255598 0.79 ALDH1A1 (0.57) AKR1C3GAAMAPTALDH1A1TP53
Benzophenone SCHEMBL27403393 0.79 MAPT (0.74) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL31050955 0.78 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL31050956 0.78 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1TP53
SCHEMBL21808808 0.78 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745154-B1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM LIGNOZYM GMBH (DE) 1998-09-16 EP claimed
EP-0845026-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL, Hans-Peter Dr. (DE) 1998-06-03 EP claimed
WO-1997048786-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL HANS PETER (DE) 1997-12-24 WO claimed