Ethylene

Ethylene

SCHEMBL8621311

C=C.C=CC(=O)NC(=O)C=C

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 2/20 0.41
FGFR4 P22455 1/20 0.39
TGM2 P21980 8/20 0.39
PSMB11 A5LHX3 1/20 0.37
PSMA7 O14818 1/20 0.37
PSMB1 P20618 1/20 0.37
PSMA1 P25786 1/20 0.37
PSMA2 P25787 1/20 0.37
PSMA3 P25788 1/20 0.37
PSMA4 P25789 1/20 0.37
PSMB8 P28062 1/20 0.37
PSMB9 P28065 1/20 0.37
PSMA5 P28066 1/20 0.37
PSMB4 P28070 1/20 0.37
PSMB6 P28072 1/20 0.37
PSMB5 P28074 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26217 0.96
SCHEMBL7165464 0.96
Methane SCHEMBL9845065 0.93 TSHR (0.50) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL3284715 0.93 TSHR (0.50) TSHRALDH1A1MAPK1TDP1LMNA
Formaldehyde SCHEMBL16146046 0.93 TSHR (0.50) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL8764886 0.87 ALDH1A1 (0.46) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL1136939 0.87 ALDH1A1 (0.52) TSHRALDH1A1MAPK1TDP1LMNA
Propene SCHEMBL22685887 0.87 TSHR (0.48) TSHRALDH1A1MAPK1TDP1LMNA
Urea SCHEMBL27709911 0.87 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL7687743 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659779-B1 Microsphere and method for production thereof FUJIMORI KOGYO CO LTD (JP) 1998-06-03 EP disclosed
US-5635574-A DISSOLVING A MONOMERIC MIXTURE OF ETHYLENICALLY UNSATURATED AMIDE AND A CROSSLINKING AGENT IN AN ALCOHOLIC SOLVENT IN WATER IN PRESENCE OF INTIATOR AND INDUCING THE POLYMERIZATION, REMOVING THE SOLVENT FUJIMORO KOGYO CO., LTD. (JP) 1997-06-03 US disclosed
EP-0659779-A2 Microsphere and method for production thereof FUJIMORI KOGYO CO., LTD. (JP) 1995-06-28 EP disclosed