SCHEMBL8621374

SCHEMBL8621374

CCCCCCc1ccc(N=Nc2ccc(OCCCC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
ALDH1A1 P00352 2/20 0.61
LMNA P02545 2/20 0.61
MEN1 O00255 1/20 0.61
USP2 O75604 1/20 0.61
MAPK1 P28482 1/20 0.61
CASP1 P29466 1/20 0.61
KMT2A Q03164 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
SLCO1B3 Q9NPD5 1/20 0.61
SLCO1B1 Q9Y6L6 1/20 0.61
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.51
NR5A1 Q13285 1/20 0.50
PLA2G4A P47712 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
ESR1 P03372 2/20 0.49
ADRA2A P08913 2/20 0.49
ADORA3 P0DMS8 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621372 1.00 CYP3A4 (0.61) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL18405976 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL31542560 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL19996602 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL5188564 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL5188570 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL19996603 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL31542561 0.98 LMNA (0.60) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL19930174 0.97 LMNA (0.58) CYP3A4ALDH1A1LMNAMEN1USP2
SCHEMBL10623904 0.95 LMNA (0.56) CYP3A4ALDH1A1LMNAMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843197-A2 Liquid crystal device, display apparatus using same and display method using same CANON KABUSHIKI KAISHA (JP) 1998-05-20 EP disclosed
EP-0561389-B1 Display device, display apparatus using same and display method using same CANON KK (JP) 1997-01-29 EP disclosed
US-4844597-A Liquid crystal device utilizing chiral-smectic and nematic phases for thinner crystal layers CANON KABUSHIKI KAISHA (JP) 1989-07-04 US disclosed
US-4714323-A Ferroelectric liquid crystal device having chiral smectic and nematic liquid crystal composition CANON KABUSHIKI KAISHA (JP) 1987-12-22 US disclosed