Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624696 | 0.88 | FDFT1 (0.37) | FDFT1 | |
| SCHEMBL8947009 | 0.86 | FDFT1 (0.56) | FDFT1 | |
| SCHEMBL8624779 | 0.85 | FDFT1 (0.35) | FDFT1 | |
| SCHEMBL8625452 | 0.84 | AKR1C3 (0.35) | FDFT1ALDH1A1 | |
| SCHEMBL8625441 | 0.83 | ICAM1 (0.39) | FDFT1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL8623460 | 0.80 | FDFT1 (0.44) | FDFT1 | |
| SCHEMBL8947013 | 0.79 | HTR2A (0.35) | HTR2AFDFT1 | |
| SCHEMBL8621531 | 0.78 | FDFT1 (0.38) | HTR2AFDFT1 | |
| SCHEMBL8618807 | 0.77 | FDFT1 (0.56) | FDFT1 | |
| SCHEMBL8957418 | 0.77 | HRH1 (0.44) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |