Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621528 | 0.85 | HTR2A (0.40) | FDFT1 | |
| SCHEMBL8624696 | 0.85 | FDFT1 (0.37) | FDFT1 | |
| SCHEMBL8625452 | 0.81 | AKR1C3 (0.35) | FDFT1 | |
| SCHEMBL8625441 | 0.81 | ICAM1 (0.39) | FDFT1THRATHRB | |
| SCHEMBL8623460 | 0.79 | FDFT1 (0.44) | FDFT1 | |
| SCHEMBL8618807 | 0.77 | FDFT1 (0.56) | FDFT1 | |
| SCHEMBL8824820 | 0.76 | LAP3 (0.33) | — | |
| SCHEMBL8618690 | 0.75 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL8625373 | 0.75 | FDFT1 (0.56) | FDFT1 | |
| SCHEMBL8623463 | 0.73 | ACP3 (0.34) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |