Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594128 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19NPC1RAB9AL3MBTL1 | |
| SCHEMBL8621479 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AIDH1 | |
| SCHEMBL8621609 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL14514898 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP2C19NPC1RAB9AIDH1 | |
| SCHEMBL10369008 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP2C19NPC1RAB9AL3MBTL1 | |
| SCHEMBL15140950 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL3933949 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL387622 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL8549063 | 0.76 | TSHR (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AL3MBTL1 | |
| SCHEMBL11990212 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |