Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13821707 | 0.84 | CTSK (0.56) | CTSKCTSSCYP2C19CTSCALDH1A1 | |
| SCHEMBL1914803 | 0.81 | CYP2C19 (0.53) | CTSKCTSSCYP2C19MEN1KMT2A | |
| SCHEMBL1914799 | 0.81 | CYP2C19 (0.53) | CTSKCTSSCYP2C19MEN1KMT2A | |
| SCHEMBL3825012 | 0.80 | ATM (0.55) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL825959 | 0.80 | ATM (0.55) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL1186455 | 0.80 | ATM (0.55) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL844316 | 0.80 | CTSK (0.73) | CTSKCTSSCYP2C19RAB9A | |
| SCHEMBL844317 | 0.80 | CTSK (0.73) | CTSKCTSSCYP2C19RAB9A | |
| SCHEMBL2481878 | 0.80 | CTSK (0.73) | CTSKCTSSCYP2C19RAB9A | |
| SCHEMBL1163822 | 0.78 | CTSK (0.60) | CTSKCTSSMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |