Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CA12 | O43570 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | BID | P55957 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL28225619 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA9CA1 | |
| Dodecane SCHEMBL6692297 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA9CA1 | |
| Salicylic Acid SCHEMBL28366261 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KDM4ECA12CA9CA1 | |
| Salicylic Acid SCHEMBL294304 | 0.96 | ALDH1A1 (0.72) | ALDH1A1KDM4ECA12CA9CA1 | |
| Salicylic Acid SCHEMBL1003308 | 0.92 | ALDH1A1 (0.78) | ALDH1A1KDM4ECA12CA9CA1 | |
| Cetostearyl Alcohol SCHEMBL27785964 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA9CA1 | |
| Salicylic Acid SCHEMBL28538392 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA9CA1 | |
| Cetyl Alcohol SCHEMBL27940954 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM4ECA12CA9CA1 | |
| Tetrabuthylammonium SCHEMBL5989289 | 0.91 | KDM4E (0.60) | ALDH1A1KDM4ECA12CA9CA1 | |
| Salicylic Acid SCHEMBL27304495 | 0.91 | KDM4E (0.60) | ALDH1A1KDM4ECA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843719-A1 | DETERGENT COMPOSITIONS CONTAINING AMINE AND SPECIALLY SELECTED PERFUMES | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006235-A1 | DETERGENT COMPOSITIONS CONTAINING AMINE AND SPECIALLY SELECTED PERFUMES | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-20 | — | — | WO | disclosed |