Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21972575 | 0.86 | ALDH1A1 (0.72) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL6323603 | 0.83 | KMT2A (0.68) | TSHRRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9671985 | 0.83 | TSHR (0.77) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL2840870 | 0.81 | TSHR (0.74) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL2840873 | 0.81 | TSHR (0.74) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL11122026 | 0.80 | CA12 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL491660 | 0.80 | TSHR (0.72) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL6691604 | 0.80 | TSHR (0.72) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL21639596 | 0.80 | TSHR (0.77) | TSHRRAB9AGAAMEN1KMT2A | |
| SCHEMBL7141724 | 0.80 | TSHR (0.72) | TSHRRAB9AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115573-A1 | PYRIDAZINE-BASED PYRIDINE DERIVATIVES AS BIOLOGICALLY ACTIVE AGENTS | IMRAN MOHD (SA) | 2025-04-10 | — | — | US | disclosed |
| US-5716446-A | PRINTING INK; TONERS; POWDER COATING | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| US-5698705-A | BASED ON AMINOBENZIMIDAZOLONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115573-A1 | PYRIDAZINE-BASED PYRIDINE DERIVATIVES AS BIOLOGICALLY ACTIVE AGENTS | HRH4, HRH3, CBR3 | TSHR 646/4885RAB9A 3243/4885GAA 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.