Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623300 | 0.95 | ESR1 (0.50) | ESR1ESR2ADRA2AADORA3TACR2 | |
| SCHEMBL7195929 | 0.92 | ESR1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL7200829 | 0.86 | ESR1 (0.69) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8646182 | 0.86 | HPGD (0.63) | ESR1ESR2ADRA2AADORA3TACR2 | |
| SCHEMBL13804557 | 0.84 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL13804556 | 0.84 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8627409 | 0.83 | ESR1 (0.59) | ESR1ESR2KDM4EALDH1A1LMNA | |
| SCHEMBL8623880 | 0.82 | PSMB11 (0.59) | ESR1ESR2ALDH1A1LMNATP53 | |
| SCHEMBL7197962 | 0.81 | TRPV1 (0.56) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8624190 | 0.80 | HDAC1 (0.52) | ESR1ESR2PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |