Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | MATK | P42679 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 5/20 | 0.46 |
| ▸ | TOP2A | P11388 | 8/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.43 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088627 | 0.96 | PIM3 (0.52) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL9087988 | 0.92 | ALDH1A1 (0.52) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10509763 | 0.92 | ALDH1A1 (0.52) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL9088336 | 0.92 | PIM3 (0.48) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL9089065 | 0.90 | PIM3 (0.50) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10683743 | 0.90 | POLB (0.52) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| Hydrochloric Acid SCHEMBL9688844 | 0.89 | POLB (0.52) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL8110587 | 0.85 | POLB (0.61) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL9087532 | 0.85 | KDM4E (0.46) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL7997606 | 0.83 | RPS6KB1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2815119-B2 | — | — | 1998-10-27 | — | — | JP | claimed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | claimed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | claimed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | claimed |
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |