SCHEMBL8622065

SCHEMBL8622065

BOCCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
IDO1 P14902 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
HCAR2 Q8TDS4 1/20 0.42
MAOA P21397 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL198134 0.78 TSHR (0.52) CA1CA2CA9IDO1ALDH1A1
SCHEMBL6341147 0.78 ALDH1A1 (0.52) CA1CA2CA9IDO1ALDH1A1
SCHEMBL7038839 0.76 CA1 (0.50) CA1CA2CA9IDO1ALDH1A1
SCHEMBL21987926 0.76 ALDH1A1 (0.50) CA1CA2CA9IDO1ALDH1A1
SCHEMBL5946547 0.74 CA1 (0.48) CA1CA2CA9IDO1ALDH1A1
SCHEMBL5733114 0.74 CA1 (0.48) CA1CA2CA9IDO1ALDH1A1
SCHEMBL523683 0.74 CA1 (0.48) CA1CA2CA9IDO1ALDH1A1
SCHEMBL538855 0.74 IDO1 (0.74) CA1CA2CA9IDO1ALDH1A1
SCHEMBL1140622 0.74 TDP1 (0.52) CA1CA2CA9IDO1ALDH1A1
SCHEMBL538854 0.74 CA1 (0.48) CA1CA2CA9IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5852221-A Optically active β-aminoalkoxyborane complex NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1998-12-22 US disclosed
US-5808098-A REDUCING AGENT FROM AMINOALCOHOL NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1998-09-15 US disclosed
US-5786485-A REACTING OPTICALLY ACTIVE BETA-AMINOALCOHOL WITH BORANE REAGENT TO PRODUCE OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEX NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-07-28 US disclosed
US-5739347-A REDUCING AGENTS FOR DECARBONYLATION NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1998-04-14 US disclosed