Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 8/20 | 0.73 |
| ▸ | PARP1 | P09874 | 8/20 | 0.68 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
| ▸ | AKT1 | P31749 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 1/20 | 0.68 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.68 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.60 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980737 | 0.93 | ACVR1 (0.67) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL13820309 | 0.91 | PARP1 (0.78) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL6869415 | 0.87 | ACVR1 (0.63) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL3731351 | 0.87 | ACVR1 (0.60) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL12441754 | 0.86 | PARP1 (0.60) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL13718572 | 0.84 | PARP1 (0.63) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL7980108 | 0.84 | QPCT (0.65) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL28224560 | 0.84 | IP6K1 (0.62) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL3739920 | 0.84 | IP6K1 (0.61) | ACVR1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL30669818 | 0.84 | QPCT (0.65) | ACVR1PARP1CHEK1PIM1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |