Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624994 | 0.90 | KDM4E (0.40) | HIF1AALDH1A1KDM4EKDR | |
| SCHEMBL8624613 | 0.86 | PLA2G1B (0.38) | HIF1ASMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL5257827 | 0.86 | HIF1A (0.36) | HIF1ASMN1; SMN2KDM4EKDR | |
| SCHEMBL8624971 | 0.86 | HIF1A (0.36) | HIF1ASMN1; SMN2KDM4EKDR | |
| SCHEMBL8624045 | 0.81 | — | — | |
| SCHEMBL9056021 | 0.76 | HIF1A (0.38) | HIF1A | |
| SCHEMBL9056334 | 0.76 | HIF1A (0.37) | HIF1ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL18292032 | 0.76 | HIF1A (0.39) | HIF1AALDH1A1 | |
| SCHEMBL19199357 | 0.73 | HIF1A (0.36) | HIF1AMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL23971814 | 0.73 | S1PR1 (0.39) | HIF1AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844993-A2 | PESTICIDAL INDAZOLE DERIVATIVES | Novartis AG (CH) | 1998-06-03 | — | — | EP | claimed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | claimed |
| EP-0844993-A2 | PESTICIDAL INDAZOLE DERIVATIVES | Novartis AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |