Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257827 | 1.00 | HIF1A (0.36) | HIF1AKDRKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL8622190 | 0.86 | HIF1A (0.33) | HIF1AKDRKDM4ESMN1; SMN2 | |
| SCHEMBL8624994 | 0.85 | KDM4E (0.40) | HIF1AKDRKDM4EHTR3A | |
| SCHEMBL5256221 | 0.83 | HIF1A (0.41) | HIF1AKDRHTR3AOPRL1PPARG | |
| SCHEMBL5256222 | 0.83 | HIF1A (0.41) | HIF1AKDRHTR3AOPRL1PPARG | |
| SCHEMBL5259659 | 0.77 | HIF1A (0.43) | HIF1AKDRHTR3A | |
| SCHEMBL8624613 | 0.77 | PLA2G1B (0.38) | HIF1ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8624045 | 0.76 | — | — | |
| SCHEMBL9056334 | 0.75 | HIF1A (0.37) | HIF1AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL7463027 | 0.74 | HIF1A (0.40) | HIF1AKDM4ESMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844993-A2 | PESTICIDAL INDAZOLE DERIVATIVES | Novartis AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997007103-A2 | PESTICIDAL INDAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1997-02-27 | — | — | WO | disclosed |