Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618631 | 0.90 | L3MBTL1 (0.40) | NISCHL3MBTL1ALDH1A1LMNAFABP4 | |
| SCHEMBL8622457 | 0.85 | L3MBTL1 (0.40) | NISCHKDM4EL3MBTL1ATMTSHR | |
| SCHEMBL8620420 | 0.82 | HIF1A (0.44) | KDM4EALDH1A1LMNAATMHIF1A | |
| SCHEMBL8622276 | 0.81 | PPARD (0.43) | NISCHHIF1A | |
| SCHEMBL8617222 | 0.81 | CDK4 (0.44) | L3MBTL1ALDH1A1FFAR4CDK4CCND1 | |
| SCHEMBL8623908 | 0.80 | HIF1A (0.46) | KDM4EL3MBTL1HIF1A | |
| SCHEMBL8622477 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1LMNATSHRHIF1A | |
| SCHEMBL8617436 | 0.78 | HIF1A (0.46) | NISCHKDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL8617439 | 0.78 | HIF1A (0.46) | NISCHKDM4EL3MBTL1ALDH1A1HTT | |
| SCHEMBL8619537 | 0.77 | HIF1A (0.44) | NISCHKDM4EL3MBTL1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |