Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976698 | 1.00 | TSHR (0.36) | TSHREPHX2TBXA2RPTGER4TDP1 | |
| SCHEMBL862240 | 1.00 | TSHR (0.36) | TSHREPHX2TBXA2RPTGER4TDP1 | |
| SCHEMBL11536982 | 1.00 | TSHR (0.36) | TSHREPHX2TBXA2RPTGER4TDP1 | |
| SCHEMBL9976696 | 0.81 | PTGER2 (0.33) | EPHX2TBXA2RPTGER4PTGER2LMNA | |
| SCHEMBL861989 | 0.81 | PTGER2 (0.33) | EPHX2TBXA2RPTGER4PTGER2LMNA | |
| SCHEMBL12087933 | 0.81 | TSHR (0.40) | TSHREPHX2TBXA2RPTGER4TDP1 | |
| SCHEMBL11449596 | 0.81 | ALDH1A1 (0.37) | TSHREPHX2TBXA2RPTGER4PTGER2 | |
| SCHEMBL9976703 | 0.81 | ALDH1A1 (0.37) | TSHREPHX2TBXA2RPTGER4PTGER2 | |
| SCHEMBL862426 | 0.81 | ALDH1A1 (0.37) | TSHREPHX2TBXA2RPTGER4PTGER2 | |
| SCHEMBL11449595 | 0.81 | ALDH1A1 (0.37) | TSHREPHX2TBXA2RPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143316-B2 | Method for treating peripheral vascular diseases | SUCAMPO AG (CH) | 2012-03-27 | — | — | US | disclosed |