Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622260 | 0.88 | HSP90AA1 (0.45) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL8620761 | 0.85 | KDM4E (0.49) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL8623627 | 0.85 | HSP90AA1 (0.42) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL9052382 | 0.84 | KDM4E (0.39) | HSP90AA1CRHBPCRHR2KDM4ELMNA | |
| SCHEMBL7358973 | 0.82 | HSP90AA1 (0.49) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL8622309 | 0.81 | HSP90AA1 (0.42) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL8623668 | 0.81 | HPGD (0.47) | KDM4EHPGDLMNANCEH1L3MBTL1 | |
| SCHEMBL8617763 | 0.79 | HSP90AA1 (0.46) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL8622264 | 0.75 | HSP90AA1 (0.41) | HSP90AA1CRHBPCRHR2TSHRKDM4E | |
| SCHEMBL27338315 | 0.74 | HSP90AA1 (0.49) | HSP90AA1CRHBPCRHR2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |