Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746256 | 0.81 | KMT2A (0.35) | KMT2AKEAP1NFE2L2POLBLMNA | |
| SCHEMBL7781069 | 0.79 | ALDH1A1 (0.36) | KMT2ANOS2KEAP1NFE2L2POLB | |
| SCHEMBL7781065 | 0.68 | KMT2A (0.38) | KMT2ANOS2KEAP1NFE2L2POLB | |
| SCHEMBL9249999 | 0.67 | PLG (0.43) | KMT2ANOS2LMNANOS3NOS1 | |
| SCHEMBL27865730 | 0.66 | KMT2A (0.43) | KMT2AKEAP1NFE2L2POLBLMNA | |
| SCHEMBL28409477 | 0.66 | MEN1 (0.34) | KMT2AKEAP1NFE2L2ALDH1A1MEN1 | |
| SCHEMBL1345211 | 0.66 | ALDH1A1 (0.39) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL11620703 | 0.66 | KMT2A (0.41) | KMT2APOLBLMNAALDH1A1KDM4E | |
| SCHEMBL8760246 | 0.65 | — | — | |
| SCHEMBL13162613 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10067766-A | — | — | None | — | — | JP | disclosed |
| JP-10045755-A | — | — | None | — | — | JP | disclosed |
| JP-H1067766-A | PRODUCTION OF TETRAHYDROFURAN DERIVATIVE | MITSUI PETROCHEM IND LTD | 1998-03-10 | — | — | JP | disclosed |
| JP-H1045755-A | PRODUCTION OF 1-(TETRAHYDROFURYL)METHYL-2-NITROIMINOHEXAHYDRO-1,3,5-TRIAZINE COMPOUND | MITSUI PETROCHEM IND LTD | 1998-02-17 | — | — | JP | disclosed |