Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878839 | 0.90 | GCGR (0.39) | GCGRDHODH | |
| SCHEMBL8878405 | 0.86 | DHODH (0.34) | DHODH | |
| SCHEMBL8877663 | 0.86 | GCGR (0.35) | GCGR | |
| SCHEMBL8877560 | 0.85 | PRKAA2 (0.37) | DHODH | |
| SCHEMBL8878285 | 0.83 | GCGR (0.36) | GCGR | |
| SCHEMBL8877412 | 0.82 | DHODH (0.34) | GCGRDHODH | |
| SCHEMBL8877489 | 0.82 | HMGCR (0.42) | — | |
| SCHEMBL8875665 | 0.81 | GCGR (0.37) | GCGRDHODH | |
| SCHEMBL8877553 | 0.80 | HMGCR (0.42) | DHODH | |
| SCHEMBL8877109 | 0.79 | HMGCR (0.43) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |