Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878839 | 0.91 | GCGR (0.39) | GCGRDHODHHMGCR | |
| SCHEMBL8902214 | 0.87 | GCGR (0.39) | GCGRDHODHFABP4 | |
| SCHEMBL8878758 | 0.85 | GCGR (0.34) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8876685 | 0.84 | GCGR (0.37) | GCGRDHODHFABP4 | |
| SCHEMBL8900797 | 0.82 | ADORA3 (0.35) | DHODHFABP4 | |
| SCHEMBL8877066 | 0.82 | HMGCR (0.41) | HMGCR | |
| SCHEMBL8622337 | 0.81 | GCGR (0.34) | GCGRDHODH | |
| SCHEMBL8878908 | 0.80 | GCGR (0.41) | GCGRDHODH | |
| SCHEMBL8900007 | 0.78 | DHODH (0.37) | GCGRDHODH | |
| SCHEMBL8876885 | 0.78 | GCGR (0.39) | GCGRDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |