Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976701 | 1.00 | POLB (0.37) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL862429 | 1.00 | POLB (0.37) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL9976695 | 0.91 | ALDH1A1 (0.34) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL12087973 | 0.86 | POLB (0.39) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL18965531 | 0.85 | POLB (0.38) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL11456639 | 0.80 | ALDH1A1 (0.31) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL11456636 | 0.80 | ALDH1A1 (0.31) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL861932 | 0.80 | PTGER2 (0.36) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL9976702 | 0.80 | PTGER2 (0.36) | POLBALDH1A1LMNAPGRMAPT | |
| SCHEMBL9980022 | 0.79 | POLB (0.39) | POLBALDH1A1LMNAPGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143316-B2 | Method for treating peripheral vascular diseases | SUCAMPO AG (CH) | 2012-03-27 | — | — | US | disclosed |