Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | HINT1 | P49773 | 5/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | TYMP | P19971 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622459 | 1.00 | POLB (0.67) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL367384 | 0.91 | POLB (0.65) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL16359949 | 0.89 | POLB (0.70) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL338650 | 0.89 | POLB (0.70) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL5347882 | 0.89 | POLB (0.63) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL23352540 | 0.89 | POLB (0.54) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL3893075 | 0.89 | POLB (0.54) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL17001491 | 0.89 | POLB (0.54) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL2775081 | 0.89 | POLB (0.54) | POLBHINT1P2RY2P2RY4P2RY6 | |
| SCHEMBL18769456 | 0.89 | POLB (0.54) | POLBHINT1P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756704-A | Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-26 | — | — | US | disclosed |