SCHEMBL8622709

SCHEMBL8622709

O=S(=O)([O-])c1ccccc1.[Rb+]

nearest known ligand 0.55

Known targets — ChEMBL curated mechanism

CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.55
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
HSD17B10 Q99714 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50
CA13 Q8N1Q1 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
DUSP3 P51452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31214894 0.97 HTR6 (0.52) HTR6CA1CA2ALDH1A1CA12
SCHEMBL1981609 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL20533807 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL6439075 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL587792 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL3409456 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL284565 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL20583771 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL20533805 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12
SCHEMBL2042047 0.94 HTR6 (0.55) HTR6CA1CA2ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118844448-A Preparation method of long-acting antibacterial liquid 孙国明 2024-10-29 CN claimed
CN-115433376-A Preparation method of long-acting disinfection and sterilization fabric or fiber 孙国明 2022-12-06 CN claimed
CN-115433376-A Preparation method of long-acting disinfection and sterilization fabric or fiber 孙国明 2022-12-06 CN disclosed
EP-0543340-B1 Process for preparing lactones TOSOH CORP (JP) 1998-05-20 EP disclosed
US-5502217-A MULTISTAGE PROCESS WITH HYDROGENATION OF MALEIC ACID OR SUCCINIC ACID IN THE PRESENCE OF METAL TO FORM BUTYROLACTONE TOSOH CORPORATION (JP) 1996-03-26 US disclosed
EP-0543340-A1 Process for preparing lactones Tosoh Corporation (JP) 1993-05-26 EP disclosed
US-3985797-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3985796-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3931295-A Hydroxylation of aromatic compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-01-06 US disclosed