Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 3/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8627100 | 0.89 | SMN1; SMN2 (0.38) | KDM1ADRD2DRD4HTR1ADRD3 | |
| SCHEMBL8622811 | 0.78 | OPRL1 (0.35) | OPRL1OGFRL1ITGB3ITGA2BKDM1A | |
| SCHEMBL8625155 | 0.72 | MAPK14 (0.38) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8627104 | 0.69 | SMN1; SMN2 (0.37) | DRD2DRD4HTR1ADRD3 | |
| SCHEMBL8622807 | 0.67 | CARM1 (0.37) | ITGB3ITGA2BKDM1A | |
| SCHEMBL8642800 | 0.66 | KDM1A (0.33) | ITGB3ITGA2BKDM1A | |
| SCHEMBL8624504 | 0.65 | DGAT1 (0.39) | ITGB3ITGA2B | |
| SCHEMBL8624503 | 0.65 | DGAT1 (0.39) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8624210 | 0.64 | DGAT1 (0.39) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8624214 | 0.64 | DGAT1 (0.39) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |