SCHEMBL8622862

SCHEMBL8622862

CCCCCCCC/C=C\CCCCCCCCNC(=O)CC(=O)Nc1cc(O)c(O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.53
GPR119 Q8TDV5 1/20 0.52
EPHX2 P34913 2/20 0.51
PSMB11 A5LHX3 1/20 0.51
PSMA7 O14818 1/20 0.51
PSMB1 P20618 1/20 0.51
PSMA1 P25786 1/20 0.51
PSMA2 P25787 1/20 0.51
PSMA3 P25788 1/20 0.51
PSMA4 P25789 1/20 0.51
PSMB8 P28062 1/20 0.51
PSMB9 P28065 1/20 0.51
PSMA5 P28066 1/20 0.51
PSMB4 P28070 1/20 0.51
PSMB6 P28072 1/20 0.51
PSMB5 P28074 1/20 0.51
PSMB10 P40306 1/20 0.51
PSMB3 P49720 1/20 0.51
PSMB2 P49721 1/20 0.51
PSMA6 P60900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624295 0.93 TRPV1 (0.51)
SCHEMBL8622678 0.93 TRPV1 (0.51)
SCHEMBL8624167 0.93 TRPV1 (0.51)
SCHEMBL8621432 0.88 GPR119 (0.61) GPR119PSMB11PSMA7PSMB1PSMA1
SCHEMBL8622806 0.87 EPHX2 (0.52) SLC6A5GPR119EPHX2PSMB11PSMA7
SCHEMBL8622058 0.83 PSMB11 (0.74) SLC6A5EPHX2PSMB11PSMA7PSMB1
SCHEMBL8622046 0.83 PSMB11 (0.74) SLC6A5EPHX2PSMB11PSMA7PSMB1
SCHEMBL8626443 0.80 TRPV1 (0.63) GPR119EPHX2KDM4ENPC1GMNN
SCHEMBL8626992 0.80 TRPV1 (0.63) GPR119EPHX2KDM4ENPC1GMNN
SCHEMBL8628167 0.80 TRPV1 (0.63) GPR119EPHX2KDM4ENPC1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed