Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840781 | 0.79 | CYP3A4 (0.54) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL2575749 | 0.79 | CYP3A4 (0.54) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL4451153 | 0.78 | CTSD (0.51) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL2577715 | 0.74 | CYP3A4 (0.41) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL13825589 | 0.74 | CYP3A4 (0.57) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL2576894 | 0.74 | CYP3A4 (0.57) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL5689588 | 0.72 | CYP3A4 (0.60) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL6224163 | 0.72 | CYP3A4 (0.60) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL3041808 | 0.72 | CYP3A4 (0.50) | CTSDCYP3A4LMNAUSP2CYP2D6 | |
| SCHEMBL13219375 | 0.71 | CYP3A4 (0.55) | CTSDCYP3A4LMNAUSP2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786483-A | α-and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1998-07-28 | — | — | US | claimed |