Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539972 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10930589 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16124200 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL31399502 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL200311 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1143253 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL25304378 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28500270 | 1.00 | DUT (0.37) | DUTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL334934 | 0.98 | DUT (0.38) | DUTCYP4F2CYP4A11 | |
| SCHEMBL571057 | 0.91 | DUT (0.39) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029923-A1 | PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | claimed |
| US-5811568-A | PHOSPHORYLATION | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| WO-1995029923-A1 | PROCESS FOR THE PREPARATION OF MONO- AND BIS(PHOSPHOCHOLINE) DERIVATIVES WHICH HAVE ANTIFUNGAL ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | disclosed |