Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618944 | 0.83 | FNTA (0.57) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL8618952 | 0.83 | FNTA (0.57) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL8615982 | 0.82 | FNTA (0.56) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL8615976 | 0.82 | FNTA (0.56) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL1680520 | 0.76 | TAAR1 (0.57) | CYP1A2CYP2A6SIGMAR1HIF1AKDM4E | |
| SCHEMBL8616037 | 0.75 | PDPK1 (0.68) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL8616042 | 0.75 | PDPK1 (0.68) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| SCHEMBL8615974 | 0.74 | FNTA (0.61) | FNTAFNTBPDPK1CYP1A2HDAC1 | |
| Hydrochloric Acid SCHEMBL6559137 | 0.74 | TAAR1 (0.55) | CYP1A2CYP2A6SIGMAR1HIF1AKDM4E | |
| SCHEMBL5236795 | 0.73 | CYP1A2 (0.68) | FNTAFNTBPDPK1CYP1A2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |