Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.57 |
| ▸ | FNTB | P49356 | 1/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618944 | 1.00 | FNTA (0.57) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL8615982 | 0.86 | FNTA (0.56) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL8615976 | 0.86 | FNTA (0.56) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL8622997 | 0.83 | FNTA (0.54) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL29572084 | 0.79 | ALDH1A1 (0.53) | HDAC8KDM4ECYP3A4MAPTFFAR1 | |
| SCHEMBL21486330 | 0.79 | ALDH1A1 (0.53) | HDAC8KDM4ECYP3A4MAPTFFAR1 | |
| SCHEMBL8616042 | 0.78 | PDPK1 (0.68) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL8616037 | 0.78 | PDPK1 (0.68) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL8615974 | 0.78 | FNTA (0.61) | FNTAFNTBPDPK1CYP1A2CYP2A6 | |
| SCHEMBL2813151 | 0.77 | FFAR1 (0.53) | HDAC1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |