SCHEMBL8623129

SCHEMBL8623129

CCOC(=O)CN(CC(=O)OC)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.51
PPARG P37231 1/20 0.48
PPID Q08752 1/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624227 0.93 SMN1; SMN2 (0.57) SMN1; SMN2PPARGPPIDALDH1A1MEN1
SCHEMBL8627738 0.90 POLB (0.46) ALDH1A1MEN1KMT2APOLB
SCHEMBL4517708 0.89 SMN1; SMN2 (0.53) SMN1; SMN2PPARGPPIDALDH1A1MEN1
SCHEMBL14508465 0.87 SMN1; SMN2 (0.51) SMN1; SMN2PPARGPPIDALDH1A1MEN1
SCHEMBL8089314 0.87 SMN1; SMN2 (0.58) SMN1; SMN2PPARGPPIDALDH1A1MEN1
SCHEMBL12762278 0.87 SMN1; SMN2 (0.54) SMN1; SMN2PPARGPPIDALDH1A1MEN1
SCHEMBL6486619 0.87 SMN1; SMN2 (0.54) SMN1; SMN2PPARGALDH1A1MEN1KMT2A
SCHEMBL3841166 0.85 TDP1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2APOLB
SCHEMBL705309 0.85 MEN1 (0.51) SMN1; SMN2ALDH1A1MEN1KMT2AGAA
SCHEMBL13603924 0.84 ALDH1A1 (0.51) ALDH1A1KMT2AGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0864615-A1 Azodyesuff mixtures Ciba SC Holding AG (CH) 1998-09-16 EP disclosed