⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023108 | 0.88 | — | — | |
| SCHEMBL13404962 | 0.86 | — | — | |
| SCHEMBL16424464 | 0.86 | — | — | |
| SCHEMBL1129493 | 0.85 | USP2 (0.33) | — | |
| SCHEMBL16112710 | 0.81 | EPHX1 (0.33) | — | |
| SCHEMBL15564388 | 0.81 | — | — | |
| SCHEMBL18134202 | 0.78 | — | — | |
| SCHEMBL187063 | 0.78 | — | — | |
| SCHEMBL109050 | 0.78 | EPHX1 (0.35) | — | |
| SCHEMBL773239 | 0.78 | OPRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585678-B1 | Process of preparing reduction products of 4-hydroxybutyric acid derivatives | BASF AG (DE) | 1998-06-17 | — | — | EP | claimed |
| US-5371242-A | Catalytic hydrogenation of 4-hydroxybutyric acid to give tetrahydrofurans or diols | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |
| EP-0585678-A2 | Process of preparing reduction products of 4-hydroxybutyric acid derivatives | BASF Aktiengesellschaft (DE) | 1994-03-09 | — | — | EP | claimed |
| EP-4735438-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | Merck Patent GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006783-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | MERCK PATENT GMBH (DE) | 2025-01-02 | — | — | WO | disclosed |
| EP-3694331-A1 | INDAZOLYL-SPIRO[2.3]HEXANE-CARBONITRILE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme Corp. (US) | 2020-08-19 | — | — | EP | disclosed |
| WO-2019074810-A1 | INDAZOLYL-SPIRO[2.3]HEXANE-CARBONITRILE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2019-04-18 | — | — | WO | disclosed |
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2586778-A2 | Pyridazinone derivatives useful as glucan synthase inhibitors | Merck Sharp & Dohme Corp. (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2008035086-A2 | SYNTHESIS OF LEUKOTRIENE COMPOUNDS | ALMAC SCIENCES LIMITED (GB) | 2008-03-27 | — | — | WO | disclosed |
| EP-0585678-B1 | Process of preparing reduction products of 4-hydroxybutyric acid derivatives | BASF AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5371242-A | Catalytic hydrogenation of 4-hydroxybutyric acid to give tetrahydrofurans or diols | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0585678-A2 | Process of preparing reduction products of 4-hydroxybutyric acid derivatives | BASF Aktiengesellschaft (DE) | 1994-03-09 | — | — | EP | disclosed |