Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965595 | 0.84 | HTT (0.48) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL28212012 | 0.82 | HTT (0.46) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL17035462 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL14330807 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL20501494 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL12845027 | 0.78 | MAPK1 (0.46) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL19697164 | 0.77 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL6497498 | 0.76 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL18736915 | 0.76 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL12994501 | 0.75 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8128393-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080131692-A1 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |