Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841534 | 1.00 | REN (0.55) | REN | |
| SCHEMBL12536070 | 1.00 | REN (0.55) | REN | |
| SCHEMBL840375 | 0.91 | REN (0.56) | REN | |
| SCHEMBL4519855 | 0.91 | REN (0.56) | REN | |
| SCHEMBL4527767 | 0.91 | REN (0.56) | REN | |
| SCHEMBL12555599 | 0.88 | REN (0.68) | REN | |
| SCHEMBL13606788 | 0.87 | REN (0.54) | REN | |
| SCHEMBL862115 | 0.85 | REN (0.59) | REN | |
| SCHEMBL8905075 | 0.85 | REN (0.57) | REN | |
| SCHEMBL8905079 | 0.85 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143416-B2 | Alternative synthesis of renin inhibitors and intermediates thereof | NOVARTIS AG (CH) | 2012-03-27 | — | — | US | disclosed |
| US-8143416-B2 | Alternative synthesis of renin inhibitors and intermediates thereof | NOVARTIS AG (CH) | 2012-03-27 | — | — | US | disclosed |