Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620838 | 0.81 | — | — | |
| SCHEMBL8407425 | 0.78 | POLB (0.33) | CYP19A1MAPTPOLBHSD17B3 | |
| SCHEMBL8623526 | 0.73 | CYP19A1 (0.35) | CYP19A1MAPTPOLBHSD17B3 | |
| SCHEMBL18093964 | 0.61 | CYP19A1 (0.34) | CYP19A1MAPTPOLBABCC4STS | |
| SCHEMBL14564194 | 0.58 | ESR2 (0.50) | CYP19A1MAPTCYP2C9ALDH1A1MAPK1 | |
| SCHEMBL26509883 | 0.57 | HSD17B3 (0.46) | CYP19A1HSD17B3 | |
| SCHEMBL17562411 | 0.57 | CYP19A1 (0.47) | CYP19A1HSD17B3MAPK1 | |
| SCHEMBL21265273 | 0.57 | CYP19A1 (0.47) | CYP19A1HSD17B3MAPK1 | |
| SCHEMBL22727358 | 0.57 | CYP19A1 (0.47) | CYP19A1HSD17B3MAPK1 | |
| SCHEMBL20277869 | 0.56 | POLB (0.47) | CYP19A1MAPTPOLBHSD17B3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |