Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407083 | 0.82 | CYP19A1 (0.37) | POLBMAPTCYP19A1 | |
| SCHEMBL8409402 | 0.79 | CYP1B1 (0.42) | POLBMAPTCYP19A1 | |
| SCHEMBL8623528 | 0.78 | CYP19A1 (0.34) | POLBMAPTCYP19A1HSD17B3 | |
| SCHEMBL8651638 | 0.71 | MAPT (0.39) | POLBMAPTCYP19A1 | |
| SCHEMBL9174063 | 0.71 | MAPT (0.39) | POLBMAPTCYP19A1 | |
| SCHEMBL8768139 | 0.71 | MAPT (0.39) | POLBMAPTCYP19A1 | |
| SCHEMBL8407453 | 0.70 | PGR (0.34) | POLB | |
| SCHEMBL8653384 | 0.70 | MAPT (0.38) | POLBMAPTCYP19A1 | |
| SCHEMBL8410183 | 0.70 | PGR (0.32) | — | |
| SCHEMBL8654560 | 0.69 | STS (0.38) | POLBMAPTCYP19A1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |