Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GPX4 | P36969 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624194 | 1.00 | NPC1 (0.48) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL8627423 | 1.00 | NPC1 (0.48) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7197123 | 0.96 | LTB4R2 (0.45) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7197804 | 0.92 | LTA4H (0.48) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL8391756 | 0.92 | NPC1 (0.42) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7197913 | 0.92 | LTA4H (0.48) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL8756523 | 0.88 | NPC1 (0.50) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7264331 | 0.88 | NPC1 (0.50) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7264200 | 0.88 | NPC1 (0.50) | NPC1RAB9APAX8JAK2HSD17B3 | |
| SCHEMBL7269051 | 0.88 | NPC1 (0.50) | NPC1RAB9APAX8JAK2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |