Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555205 | 0.87 | ALDH1A1 (0.54) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL1784054 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| Dimethylamine SCHEMBL1788162 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL11790901 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL10333082 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL9299532 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL1782357 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL10611327 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL8753633 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTHPGDNPSR1L3MBTL1 | |
| SCHEMBL24013287 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HTTHPGDNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |