Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619554 | 0.90 | GABRR1 (0.42) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL169047 | 0.86 | GABRR1 (0.44) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL21641650 | 0.86 | GABRR1 (0.44) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL2709833 | 0.85 | ACE (0.48) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL17223885 | 0.85 | ACE (0.48) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL9249263 | 0.85 | GABRR1 (0.52) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL28799 | 0.85 | GABRR1 (0.52) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL21664518 | 0.85 | GABRR1 (0.52) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL2019219 | 0.85 | GABRR1 (0.52) | AKR1C3AKR1C1GABRR1ACESLC1A2 | |
| SCHEMBL9721284 | 0.85 | GABRR1 (0.52) | AKR1C3AKR1C1GABRR1ACESLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840802-A | HEAT RESISTANCE AND IMPACT STRENGTH FOR THERMOPLASTIC RESINS | GENERAL ELECTRIC COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| US-5306785-A | Molding materials | GENERAL ELECTRIC COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0586181-A2 | Thermoplastic polyester elastomer resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0322778-B1 | BICOMPONENT MOISTURE BARRIER POLY(ETHERIMIDE) ESTER FILMS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0554369-A1 | POLY(ALKYLENE CYCLOHEXANEDICARBOXYLATE) BINARY BLENDS | GENERAL ELECTRIC COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0537014-A2 | Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same | GENERAL ELECTRIC COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1993004124-A1 | POLY(ALKYLENE CYCLOHEXANEDICARBOXYLATE) BINARY BLENDS | GENERAL ELECTRIC COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| US-4769273-A | HAVING DIFFERENTIAL TRANSFER OF WATER VAPOR TO PREVENT BUILD-UP; TEXTILE COVERING; SURGICAL DRAPES; WATERPROOFED CLOTHING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |