SCHEMBL8619554

SCHEMBL8619554

O=C(OC(=O)C1CC(C(=O)O)C(C(=O)O)C1)C1CC(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.42
GABRR2 P28476 1/20 0.36
ACE P12821 1/20 0.34
SLC1A2 P43004 3/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GRM8 O00222 1/20 0.33
GRM6 O15303 1/20 0.33
LMNA P02545 1/20 0.33
APEX1 P27695 1/20 0.33
GRM5 P41594 1/20 0.33
PMP22 Q01453 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
GRM4 Q14833 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C1 Q04828 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8623877 0.90 AKR1C3 (0.39) GABRR1GABRR2ACESLC1A2AKR1C3
SCHEMBL16415207 0.87 GABRR1 (0.46) GABRR1GABRR2ACESLC1A2CYP2C9
SCHEMBL169047 0.85 GABRR1 (0.44) GABRR1GABRR2ACESLC1A2CYP2C19
SCHEMBL21641650 0.85 GABRR1 (0.44) GABRR1GABRR2ACESLC1A2CYP2C19
SCHEMBL168962 0.83 GABRR1 (0.46) GABRR1GABRR2SLC1A2CYP2C9CYP2C19
SCHEMBL5070654 0.83 GABRR1 (0.46) GABRR1GABRR2SLC1A2CYP2C9CYP2C19
SCHEMBL4478750 0.83 GABRR1 (0.46) GABRR1GABRR2SLC1A2CYP2C9CYP2C19
SCHEMBL23322142 0.81 ACE (0.40) GABRR1ACESLC1A2CYP2C19LMNA
SCHEMBL25635389 0.80 CHRNB2 (0.52) GABRR1
SCHEMBL6681736 0.80 GABRR1 (0.34) GABRR1GABRR2ACESLC1A2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116266033-A Photosensitive coloring composition for blue color filter, solid-state imaging element, and liquid crystal display device 东洋油墨SC控股株式会社 2023-06-20 CN disclosed
CN-115685673-A Photosensitive composition, optical filter, image display device, and solid-state imaging element 东洋油墨SC控股株式会社 2023-02-03 CN disclosed
CN-109564384-B Photosensitive coloring composition and color filter 东洋油墨SC控股株式会社 2022-09-20 CN disclosed
CN-110651013-B Water-soluble paint box for automobile KCC公司 2021-11-09 CN disclosed
US-10876016-B2 Water-based paint composition for vehicle KCC CORPORATION (KR) 2020-12-29 US disclosed
US-10767078-B2 2020-09-08 US disclosed
CN-107667154-B Water-soluble coating composition for vehicle 株式会社KCC 2020-04-14 CN disclosed
CN-110651013-A Water-soluble paint box for automobile KCC公司 2020-01-03 CN disclosed
CN-105324717-B Colored photosensitive resin composition, cured film, color filter and method for producing same, solid-state imaging element, and image display device 富士胶片株式会社 2019-12-17 CN disclosed
EP-3305865-B1 WATER SOLUBLE PAINT COMPOSITION FOR VEHICLE KCC CORP (KR) 2019-11-20 EP disclosed
US-20180163088-A1 WATER SOLUBLE PAINT COMPOSITION FOR VEHICLE KCC CORPORATION (KR) 2018-06-14 US disclosed
EP-3305865-A1 WATER SOLUBLE PAINT COMPOSITION FOR VEHICLE KCC Corporation (KR) 2018-04-11 EP disclosed
US-5840802-A HEAT RESISTANCE AND IMPACT STRENGTH FOR THERMOPLASTIC RESINS GENERAL ELECTRIC COMPANY (US) 1998-11-24 US disclosed
US-5550195-A ADDITION POLYMERS; PROTECTIVE COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 1996-08-27 US disclosed
US-5306785-A Molding materials GENERAL ELECTRIC COMPANY (US) 1994-04-26 US disclosed
EP-0537014-A2 Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same GENERAL ELECTRIC COMPANY (US) 1993-04-14 EP disclosed
EP-0322777-B1 VAPOR PERMEABLE POLY(ETHERIMIDE) ESTER ELASTOMER FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-04 EP disclosed
US-4868062-A WATERPROOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-09-19 US disclosed