Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619686 | 0.84 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8646135 | 0.79 | KMT2A (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7761926 | 0.78 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8647144 | 0.77 | KMT2A (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8645430 | 0.72 | KMT2A (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4689035 | 0.71 | KMT2A (0.57) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9273210 | 0.71 | KMT2A (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9268537 | 0.70 | KMT2A (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1010648 | 0.70 | MEN1 (0.53) | KMT2A | |
| SCHEMBL28230139 | 0.69 | CYP3A4 (0.55) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674636-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-05-20 | — | — | EP | disclosed |
| EP-0674636-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014804-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |