Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14896009 | 0.82 | LOXL2 (0.51) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL8624878 | 0.82 | PDPK1 (0.48) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL9672077 | 0.82 | PDPK1 (0.48) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL14894225 | 0.82 | PDPK1 (0.48) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL5462028 | 0.82 | PDPK1 (0.48) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL5692672 | 0.80 | PDPK1 (0.64) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL9422310 | 0.79 | PDPK1 (0.46) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL8053024 | 0.79 | PDPK1 (0.46) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL28177854 | 0.79 | PDPK1 (0.55) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL11398268 | 0.79 | PDPK1 (0.46) | PDPK1ADRA1AADRA1DADRA1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846107-A1 | STEREOSELECTIVE METHOD FOR SYNTHESIZING DOLAPHENINE | Pharmeco Laboratories, Inc. (US) | 1998-06-10 | — | — | EP | claimed |