SCHEMBL8624236

SCHEMBL8624236

CCCCCCCC/C=C\CCCCCCCCNC(=O)C(=O)Nc1ccc(O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.56
MAPT P10636 2/20 0.54
HPGD P15428 2/20 0.54
KDM4E B2RXH2 1/20 0.54
NPC1 O15118 1/20 0.54
GMNN O75496 1/20 0.54
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
IDE P14735 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MAPK1 P28482 1/20 0.54
CYP2C19 P33261 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621957 0.92 TRPV1 (0.57) MAPTHSD17B10ALOX12EPHX2TRPV1
SCHEMBL8624821 0.92 TRPV1 (0.57) MAPTHSD17B10ALOX12EPHX2TRPV1
SCHEMBL8623273 0.92 TRPV1 (0.57) MAPTHSD17B10ALOX12EPHX2TRPV1
SCHEMBL8621432 0.88 GPR119 (0.61) GPR119MAPTHPGDKDM4ENPC1
SCHEMBL8622806 0.88 EPHX2 (0.52) GPR119EPHX2PSMB11PSMA7PSMB1
SCHEMBL8621136 0.86 PSMB11 (0.66) MAPTHPGDTP53CYP1A2CYP3A4
SCHEMBL8621127 0.86 PSMB11 (0.66) MAPTHPGDTP53CYP1A2CYP3A4
SCHEMBL8626992 0.81 TRPV1 (0.63) GPR119MAPTHPGDKDM4ENPC1
SCHEMBL8626443 0.81 TRPV1 (0.63) GPR119MAPTHPGDKDM4ENPC1
SCHEMBL8628167 0.81 TRPV1 (0.63) GPR119MAPTHPGDKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed