Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 8/20 | 0.50 |
| ▸ | CALCR | P30988 | 8/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624378 | 1.00 | RAMP3 (0.50) | RAMP3CALCROPRD1OPRM1OPRK1 | |
| SCHEMBL8624738 | 0.91 | RAMP3 (0.51) | RAMP3CALCROPRD1OPRM1KEAP1 | |
| SCHEMBL8624746 | 0.91 | RAMP3 (0.51) | RAMP3CALCROPRD1OPRM1KEAP1 | |
| SCHEMBL8643257 | 0.91 | KEAP1 (0.47) | RAMP3CALCRKEAP1 | |
| SCHEMBL8643264 | 0.91 | KEAP1 (0.47) | RAMP3CALCRKEAP1 | |
| SCHEMBL30242243 | 0.91 | CXCR4 (0.53) | RAMP3CALCROPRD1OPRM1OPRK1 | |
| SCHEMBL30335608 | 0.88 | KEAP1 (0.49) | RAMP3CALCRKEAP1 | |
| SCHEMBL26186023 | 0.88 | KEAP1 (0.49) | RAMP3CALCRKEAP1 | |
| SCHEMBL26186082 | 0.88 | KEAP1 (0.49) | RAMP3CALCRKEAP1 | |
| SCHEMBL30449622 | 0.88 | KEAP1 (0.48) | RAMP3CALCRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786205-A | ISOLATED PURIFIED DNA ENCODING A POLYPEPTIDE BACTERICIDE FOR TREATING GRAMPOSITIVE BACTERIA INFECTION | THE ROCKEFELLER UNIVERSITY (US) | 1998-07-28 | — | — | US | disclosed |
| US-5616686-A | INCLUDING A SEQUENCE OF AMINO ACIDS CORRESPONDING TO THAT RESPONSIBLE FOR ANCHORING A VIRULENCE DETERMINANT PROTEIN TO THE SURFACE OF A GRAMPOSITIVE COCCAL BACTERIA | THE ROCKEFELLER UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |